To Get More Effective Drugs, We Need More Human Trials

We're optimizing the wrong steps in drug discovery.

19 hrs ago • 

Ruxandra Teslo

18

9

5

Metascience in Dangerous Times

As Macroscience relaunches, a fundamental question has been on my mind.

Dec 2 • 

Tim Hwang

22

8

4

November 2025

Relaunching Macroscience

A better science is possible

Nov 24 • 

Andrew Gerard

38

5

9

December 2024

How Scientific Incentives Stalled the Fight Against Antibiotic Resistance, and How We Can Fix It

Peptide-DB: A Million-Peptide Database to Accelerate Science

Dec 13, 2024 • 

Maxwell Tabarrok

56

4

8

November 2024

Metascience 101 - EP9: "How to Get Involved"

IN THIS EPISODE: Professor Heidi Williams, Professor Paul Niehaus, and Matt Clancy walk through academic, non-profit and private sector paths to…

Nov 5, 2024 • 

Tim Hwang

8

1

3

45:23

October 2024

Metascience 101 - EP8: "Invention vs. Diffusion"

IN THIS EPISODE: Journalist Derek Thompson and economist Eli Dourado investigate the bottlenecks standing in the way of the invention vs.

Oct 29, 2024 • 

Tim Hwang

4

2

38:47

Metascience 101 - EP7: “Science and Political Legitimacy"

IN THIS EPISODE: Journalist Dylan Matthews leads a conversation with Open Philanthropy CEO Alexander Berger, Professor Tyler Cowen, and IFP Co-CEO Caleb…

Oct 23, 2024 • 

Tim Hwang

 and 

Caleb Watney

13

1

1:10:02

Metascience 101 - EP6: “Safety and Science”

IN THIS EPISODE: Journalist Dylan Matthews sits down with Professor Tyler Cowen, Matt Clancy, and Jacob Trefethen to discuss whether there are tensions…

Oct 16, 2024 • 

Tim Hwang

8

1

55:16

Metascience 101 - EP5: "How and Why to Run an Experiment"

Listen now (58 mins) | IN THIS EPISODE: Professor Heidi Williams, Professor Paul Niehaus, Emily Oehlsen, and Jim Savage dive in on a practical “how-to…

Oct 9, 2024 • 

Tim Hwang

4

1

58:01

Metascience 101 - EP4: "ARPAs, FROs, and Fast Grants, oh my!"

IN THIS EPISODE: Stripe Press’s Tamara Winter talks through the broad range of scientific funding institutions with guests Professor Tyler Cowen, Arc…

Oct 1, 2024 • 

Tim Hwang

7

1

1:13:48

September 2024

Metascience 101 - EP3: "The Scientific Production Function"

IN THIS EPISODE: Journalist Kelsey Piper interviews Convergent Research CEO Adam Marblestone and Professor Paul Niehaus on the inputs to scientific…

Sep 25, 2024 • 

Tim Hwang

6

1

1:01:41

Announcing the Metascience 101 Podcast Series

One of the questions we get most frequently at IFP is: “Metascience seems like a really cool area of research.

Sep 17, 2024 • 

Tim Hwang

 and 

Caleb Watney

15

3

1